KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIK1
All Species:
28.79
Human Site:
T231
Identified Species:
52.78
UniProt:
P57059
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57059
NP_775490.2
783
84902
T231
F
D
G
P
N
L
P
T
L
R
Q
R
V
L
E
Chimpanzee
Pan troglodytes
XP_531484
783
84972
T231
F
D
G
P
N
L
P
T
L
R
Q
R
V
L
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544912
898
97147
A356
F
D
G
P
N
L
P
A
L
R
Q
R
V
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q60670
779
85009
T231
F
D
G
P
N
L
P
T
L
R
Q
R
V
L
E
Rat
Rattus norvegicus
Q9R1U5
776
84890
T231
F
D
G
P
N
L
P
T
L
R
Q
R
V
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511894
801
88312
T230
F
D
G
P
N
L
P
T
L
R
Q
R
V
L
E
Chicken
Gallus gallus
Q9IA88
798
88848
T230
F
D
G
P
N
L
P
T
L
R
Q
R
V
L
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
N263
F
D
G
S
T
L
Q
N
L
R
A
R
V
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569972
1398
149888
S345
F
D
G
S
T
L
Q
S
L
R
D
R
V
L
S
Honey Bee
Apis mellifera
XP_397175
718
80391
S221
F
D
G
S
T
L
Q
S
L
R
D
R
V
L
S
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
E374
F
D
G
Q
N
L
K
E
L
R
E
R
V
L
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
G27
Y
K
L
G
K
T
L
G
I
G
S
F
G
K
V
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
K148
D
Y
I
V
Q
R
D
K
M
S
E
Q
E
A
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
69.2
N.A.
81.3
81.6
N.A.
70.4
66.6
N.A.
32
N.A.
28.8
36.5
24.5
N.A.
Protein Similarity:
100
99.6
N.A.
73.6
N.A.
86.2
86.3
N.A.
77
76.6
N.A.
44
N.A.
38
50.9
39.4
N.A.
P-Site Identity:
100
100
N.A.
93.3
N.A.
100
100
N.A.
100
100
N.A.
60
N.A.
60
60
66.6
N.A.
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
100
N.A.
100
100
N.A.
60
N.A.
66.6
66.6
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.2
27.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41
42.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
85
0
0
0
0
8
0
0
0
16
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
0
0
16
0
8
0
54
% E
% Phe:
85
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
85
8
0
0
0
8
0
8
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
8
0
8
8
0
0
0
0
0
8
0
% K
% Leu:
0
0
8
0
0
85
8
0
85
0
0
0
0
85
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
62
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
54
0
0
54
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
8
0
24
0
0
0
54
8
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
85
0
85
0
0
16
% R
% Ser:
0
0
0
24
0
0
0
16
0
8
8
0
0
0
24
% S
% Thr:
0
0
0
0
24
8
0
47
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
0
85
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _